OS X

Mountain Lion and Lion

sudo killall -HUP mDNSResponder

Snow Leopard

sudo dscacheutil -flushcache

alpha01:~ tony$ vim ~/.bash_profile

export CLICOLOR=1
export LSCOLORS=GxFxCxDxBxegedabagaced

sudo launchctl load -w /System/Library/LaunchDaemons/com.apple.locate.plist